Chronic unilateral chemosis following the use of amlodipine besylate

Chronic unilateral chemosis following the use of amlodipine besylate

BACKGROUND This case report describes a patient with chronic unilateral chemosis, likely due to treatment with amlodipine besylate. CASE PRESENTATION A 52-year-old man visited the clinic with symptoms of foreign body sensation and puffiness in his right eye, which had persisted for 4 months. There were no other symptoms, such as itching and pain, in his right eye and no specific symptoms in h...

Complexation of Amlodipine Besylate with β-Cyclodextrin.

In this paper the procedure for the preparation of inclusion compounds of bioactive substance 2-[(2-aminoetoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridine dicarboxylic acid 3-ethyl-5-methyl esterbenzene sulfonate, called amlodipine besylate with β-cyclodextrin (β-CD) and their structural characterization was described. Molecular inclusion compound of amlodipine besylate is obt...

Use of Forced Degradation Studies on S-(−)-Amlodipine Besylate to Generate Information on the Degradation Products

Amlodipine is a long-acting calcium channel blocker used in the treatment of hypertension and angina pectoris. S-(−)-amlodipine besylate is a safer and longer-acting alternative to the existing racemate [1]. Although several products based on the active enantiomer have reached the market, information on its chemical, physical and thermal stability during storage is lacking [2, 3]. The objective...

Enhancement of Dissolution Properties of Amlodipine Besylate Using Liquisolid Technique

The most promising method for enhancing solubility, therefore promoting the rate of dissolution is the formation of liquisolid compacts.[2]With Liquisolid technique as described by Spireas liquid formulations such as solutions or suspensions of poorly soluble drugs in a non-volatile liquid vehicle are converted into acceptably flowing and compressible powders, by simple physical blending with s...

Stability of Extemporaneously Compounded Amlodipine Besylate Oral Suspensions.